Publications

Antibodies targeting the shared cytokine resceptor IL-1 receptor accessory protein invoke distinct mechanism to block all cytokine signaling

James K. Fields, Elin Jaensson Gyllenbäck, Marek Bogacz, Juliet Obi, Gabriel Svensson Birkedal, Kjell Sjöström, Kino Maravillas, Caitríona Grönberg, Sara Rattik, Kyle Kihn, Maria Flowers, Ally K. Smith, Nils Hansen,
Thoas Fioretos, Chau Huyhn, David Liberg, Daniel Deredge, and Eric J. Sundberg,

Fields et al., 2024, Cell Reports 43, 114099
May 28, 2024 ª 2024 The Authors. Published by Elsevier Inc.
https://doi.org/10.1016/j.celrep.2024.114099

Humanization, Radiolabeling and Biodistribution Studies of an IgG1- Type Antibody Targeting Uncomplexed PSA for Theranostic Applications

Joanna Strand, Kjell Sjöström, Urpo J. Lamminmaki, Oskar Vilhelmsson Timmermand, Sven-Erik Strand and Thuy A. Tran

Pharmaceuticals 2021, 14, 1251. https://doi.org/10.3390/ph14121251

Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia

H. Ågerstam, C. Karlsson, N. Hansen, C. Sandén, M. Askmyr, S. von Palffy, C. Högberg, M. Rissler, M. Wunderlich, G. Juliusson, J. Richter, K. Sjöström, R. Bhatia, J.C. Mulloy, M. Järås, & T. Fioretos, Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia, Proc. Natl. Acad. Sci. U.S.A. 112 (34) 10786-10791, https://doi.org/10.1073/pnas.1422749112 (2015).

Molecular Basis of Selective Cytokine Signaling Inhibition by Antibodies Targeting a Shared Receptor

Fields James K. , Kihn Kyle , Birkedal Gabriel S. , Klontz Erik H. , Sjöström Kjell , Günther Sebastian , Beadenkopf Robert , Forsberg Göran , Liberg David , Snyder Greg A. , Deredge Daniel , Sundberg Eric J. Molecular Basis of Selective Cytokine Signaling Inhibition by Antibodies Targeting a Shared Receptor. Frontiers in Immunology, Volume 12 – 2021
DOI=10.3389/fimmu.2021.779100