Humanization

Humanization

Our humanization service is based on CDR grafting into suitable human frameworks.
By maintaining the binding specificity of the non-human antibody and introducing a stable and liable human framework we help you create the next therapeutic antibody.

Innovagen offers a flexible humanization service where we customize the process and scope to suit your specific needs.

Our approach:

  • Sequence analysis and human alignment
  • Sequence liability (T-cell epitope, post-translational modifications, isomerization and fragments)
  • Structural analysis
  • Production of humanized and chimeric/original variants
  • Characterization of antibodies

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