Overview
- Name:
- Beta Amyloid 1-42
- Description:
- Beta Amyloid peptides are derived from amyloid precursor protein (APP) and are thought to play a role in the development of the senile plaques associated with Alzheimer's Disease.
- Sequence:
- DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
- 3-letter-code:
- Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
- Molecular weight:
- 4514.10
- Counter ion:
- TFA
References
Maarten E. Witte, John G.J.M. Bol, Wouter H. Gerritsen, Paul van der Valk, Benjamin Drukarch, Jack van Horssen, and Micha M.M. Wilhelmus. 2009.
Parkinson’s disease-associated parkin colocalizes with Alzheimer’s disease and multiple sclerosis brain lesions.
Neurobiology of Disease, Volume 36, Issue 3, December 2009, Pages 445-452
Govindarajan, N., Rao, P., Burkhardt, S., Sananbenesi, F., Schlüter, O. M., Bradke, F., Lu, J. and Fischer, A. (2013), Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer’s disease. EMBO Mol Med, 5: 52–63. doi: 10.1002/emmm.201201923