Overview
- Name:
- Beta Amyloid 1-42; E22G
- Synonyms:
- Arctic APP mutation
- Sequence:
- DAEFRHDSGYEVHHQKLVFFAGDVGSNKGAIIGLMVGGVVIA
- 3-letter-code:
- Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-GlyAsp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
- Molecular weight:
- 4442.04
- Counter ion:
- TFA
- Notes:
- Arctic variant; Glu 22 is replaced by a Glycine (Gly).
References
M L Giuffrida, F Caraci, B Pignataro, S Cataldo, P De Bona, V Bruno, G Molinaro, G Pappalardo, A Messina, A Palmigiano, D Garozzo, F Nicoletti, E Rizzarelli, and A Copani. 2009. ?-Amyloid Monomers Are Neuroprotective. The Journal of Neuroscience, 26 August 2009, 29(34): 10582-10587; doi: 10.1523/JNEUROSCI.1736-09.2009