Overview
- Name:
- CRAMP 1-39
- Description:
- The anti-microbial peptide CRAMP corresponds to aa 135-173 of the mouse cathelicidin like protein (MCLP).
- Synonyms:
- mCRAMP, MCLP
- Sequence:
- ISRLAGLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPEQ
- 3-letter-code:
- Ile-Ser-Arg-Leu-Ala-Gly-Leu-Leu-Arg-Lys-Gly-Gly-Glu-Lys-Ile-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-Val-Pro-Gln-Pro-Glu-Gln
- Molecular weight:
- 4419.33
- Counter ion:
- TFA
- Solubilization:
- Soluble in pure water.
References
P. Bergman, L. Johansson, H. Wan, A. Jones, R. L. Gallo, G. H. Gudmundsson, T. Hökfelt, A-B Jonsson, and B. Agerberth
Induction of the Antimicrobial Peptide CRAMP in the Blood-Brain Barrier and Meninges after Meningococcal Infection
Infect Immun. 2006;74(12):6982–6991.
M. Chromek, Z. Slamová1, P. Bergman, L. Kovács, L. Podracká, I. Ehrén, T. Hökfelt, G.H. Gudmundsson, R. L. Gallo, B. Agerberth & A. Brauner. 2006.
The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection.
Nature Medicine – 12, 636-641.