Overview
- Name:
- Apelin 13, Pyr1, human
- Description:
- Apelin, which is encoded by the APLN gene, is the endogenous ligand for the G-protein-coupled APJ receptor. It is widely expressed in various organs such as the heart, lung, kidney, liver, adipose tissue, gastrointestinal tract, brain, adrenal glands, endothelium, and human plasma. The apelin pre-proprotein peptide potentially gives rise to several active fragments. Apelin 13 is a 13 amino acid peptide fragment corresponding to the sequence 65-77. It is also found in bovine, rat, and mouse. This item has the N-terminal pyroglutamylation of Gln.
- Sequence:
- (Pyr)RPRLSHKGPMPF
- 3-letter-code:
- Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe
- Molecular weight:
- 1533.82