Name:

Wrap53 C1 biotin

Description:

Polyclonal antibody raised against a synthetic Human Wrap53 peptide that maps to the C1 region of the full length Wrap53 protein. Applications tested: Western blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC)

Synonyms:

WDR79, WD repeat domain 79, telomerase Cajal body protein 1

Host:

Rabbit

Type:

Polyclonal IgG

Purity:

Antigen specific affinity purified

Immunogen:

KLH conjugated synthetic peptide.

Notes:

Biotinylated

Garvin S, Tiefenböck K, Farnebo L, Thunell LK, Farnebo M, Roberg K. 2014.Nuclear expression of WRAP53b is associated with a positive response to radiotherapy and improved overall survival in patients with head and neck squamous cell carcinoma. Oral Oncology 51 (2015) 24–30. doi: 10.1016/j.oraloncology.2014.10.003

Mahmoudi S, Henriksson S, Weibrecht I, Smith S, Söderberg O, et al. 2010. WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies. PLoS Biol 8(11): e1000521. doi:10.1371/journal.pbio.1000521

Mahmoudi S, Henriksson S, Corcoran M, Méndez-Vidal C, Wiman KG, Farnebo M. 2009. Wrap53, a natural p53 antisense transcript required for p53 induction upon DNA damage. Mol Cell. 2009 Feb 27;33(4):462-71. doi: 10.1016/j.molcel.2009.01.028.